What is it good for?

Although approved only for ICU sedation at present, dexmedetomidine works great in the OR as a titratable sedative that has minimal respiratory depressant effects.  I recommend it for patients that you’re afraid of oversedating due to airway issues, or that you want to have be quickly responsive (eg. awake craniotomies, bariatrics, carotids, etc).  There are side effects, and they can be avoided (or minimized) by dosing carefully, and by avoiding (or minimizing) the concommitant use of other sedatives.
Here's what I've come up with for dosing.  

Suggestions for additions/improvements?  Please email the management at
© Copyright 2004,  Roy G. Soto, M.D.