Flumazenil
A 78yo female s/p laryngoscopy/bronchoscopy is confused and somnolent. The procedure lasted 15 minutes, she received no opiates, and was maintained/induced with propofol only. She did, however, receive 2mg of Versed preoperatively, after which she became heavily sedated.
- What is the differential diagnosis for delayed emergence?
- Would you treat this patient with flumazenil? Why or why not?
- What is the dose of flumazenil?
- What are the pharmacodynamic
and pharmacokinetic properties of flumazenil?
References: (note, all residents should have access to Anesthesiology articles online if they receive the journal. Many other journals are available with a USF account through MD Consult...just access it from the departmental home page)